The in vitro proliferation potential and proportion of CD133+ versus CD34+ hematopoietic stem cells

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Authors	PETERKOVÁ Martina KOUTNÁ Irena ŠIMARA Pavel STEJSKAL Stanislav TESAŘOVÁ Lenka
Year of publication	2009
Type	Article in Proceedings
Conference	Experimental Hematology, Volume 37, Number 9
MU Faculty or unit	Faculty of Informatics
Citation
Field	Genetics and molecular biology
Keywords	CD133 positive - CD34 positive - HSC
Description	To compare the populations of CD133+ and CD34+ cells from human bone marrow using flow cytometry from two perspectives. To determine which of them contains larger number of primitive hematopoietic cells and to evaluate their proliferation potential. All mentioned findings suggest that CD133+ population involves a higher percentage of primitive hematopoietic cells than the CD34+ cell population. Human bone marrow CD133+ cells offer an alternative for CD34+ cells in hematopoietic stem cell transplantation.
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