MDMA decreases sociability and aggression and increases anxiety in mouse model of agonistic behaviour
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Activitas Nervosa Superior Rediviva |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | MDMA; aggressivity; sociability; anxiety; agonistic behaviour |
| Description | We evaluated acute effects of methylen-dioxy-methamphetamine (MDMA) on agonistic behaviour in singly-housed mice on paired conflict interactions with group-housed partners. We fully confirmed the antiaggressive effects and increase of defensive-escape behaviour in aggressive mice. The analysis of timid mice brought evidence of anxiogenic effect of MDMA. |
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