Endokanabinoidní systém II - úloha v adiktivním chování, depresi a při vzniku patologií potravního chování

Title in English Endocannabinoid system - the role in adictive behaviour, depression and in pathology of eating behaviour


Year of publication 2010
Type Article in Periodical
Magazine / Source Časopis lékařů českých
Keywords endocannabinoids, endocannabinoid system, reward system, addiction, eating disorders
Description Endocannabinoid system is involved in the neurobiological mechanism underlying drug addiction in all known kinds of drugs including nicotine and alcohol. Recently, relationships between endocannabinoids and biological nature of depression and eating disorders were recognised. Polymorphisms of genes encoding CB1 receptors and genes encoding main degradating enzyme FAAH responsible for pathology in motivation and cognition were identified.

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