Metabolic ratio of dextromethorphan/dextrorphan in CYP2D6 phenotyping - identification of cut-off values in serum and corelation with urine levels

Authors

JUŘICA Jan ZENDULKA Ondřej BARTEČEK Richard ŽOURKOVÁ Alexandra FLODROVÁ Eva ZRŮSTOVÁ Jana ŠULCOVÁ Alexandra

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The results of investigation of correlation of serum and urine dextromethorphan/dextrorphan metabolic ratio in CYP2D6 phenotyping were presented. Based on genetic analysis and values of MR, cutt off values (MRdem/dor) for separating extensive, poor and intermediate metabolizers were also identfied.
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