Analysis of nuclear nestin localization in cell lines derived from neurogenic tumors.

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Authors	KRUPKOVÁ Olga LOJA Tomáš RÉDOVÁ Martina NERADIL Jakub ZITTERBART Karel ŠTĚRBA Jaroslav VESELSKÁ Renata
Year of publication	2011
Type	Article in Periodical
Magazine / Source	Tumor Biology
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	nestin;intermediate filaments;cytoskeleton;glioblastoma multiforme;neuroblastoma;medulloblastoma
Description	Using immunodetection methods, we examined nestin expression in tumor-derived cell lines obtained from 11 patients with neuroblastoma, medulloblastoma, or glioblastoma multiforme. Besides its standard cytoplasmic localization, nestin was present in the nuclei of two neuroblastoma cell lines and one medulloblastoma cell line.
Related projects:	Molecular basis of cell and tissue regulations Diagnostický a prediktivní význam molekulárně cytogenetických markerů u embryonálních nádorů dětského věku Subcelulírní lokalizace nestinu v nádorově transformovaných buňkách