Usefulness of exercise tissue doppler echocardiography for prognostic stratification of congestive heart failure patients with left ventricular systolic dysfunction
| Authors | |
|---|---|
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic |
| MU Faculty or unit | |
| Citation | |
| Web | http://biomed.papers.upol.cz/getrevsrc.php?identification=public&mag=bio&raid=259&type=fin&ver=2 |
| Doi | http://dx.doi.org/10.5507/bp.2012.014 |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | exercise echocardiography; heart failure; prognosis |
| Attached files | |
| Description | Determination of the importance of exercise tissue Doppler echocardiography in prognostic stratification of congestive heart failure patients with systolic dysfunction. Methods: 106 patients with congestive heart failure and LVEF less than 45% on optimal pharmacotherapy were included in the study. Results of resting and post-exercise echocardiography, cardiopulmonary exercise test and serum BNP levels were available for all patients. Two patient groups were constituted, based on the prognostic classification. Group I contained 21 patients with poor prognosis (defined by predicted value of pVO2 < 76% together with both VE/VCO2 slope > 32.7 and BNP > 210 pg/ml) and group II with 85 patients who did not meet the criteria. Results: The patient groups significantly differed in indexed volume of left atrium, mitral regurgitation severity, rest and post-exercise systolic velocity of mitral annulus and in rest and post-exercise E/Em. Multivariate analysis identified E/Em as the only independent predictor of prognosis. E/Em at rest (post-exercise) more than 16.6 (more than 18.7) defined poor prognosis with sensitivity of 71% (86%) and specificity of 71% (71%). Conclusion: Our study suggests usefulness of exercise tissue Doppler echocardiography for prognostic stratification of patients with congestive heart failure with possible superiority to resting parameters. |