Tranzitorní hyperfosfatazemie
| Title in English | Transient hyperphosphatasemia |
|---|---|
| Authors | |
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Pediatrie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Paediatry |
| Keywords | alkaline phosphatase; transient hyperphosphatasemia; childhood |
| Description | Transient hyperphosphatasemia (TH) of infancy and childhood is a temporary and isolated increase of serum alkaline phosphatase (ALP-s) activity occurring without obvious cause usually during the first five years of life. The diagnosis of TH is established after finding of a transient but marked ALP-s elevation in the absence of clinical or laboratory findings of bone or liver disease. ALP-s returns to normal in a few months. TH has not been found to be life-threatening and is classified as a benign phenomenon. We report a clinical case of a toddler with TH and a literature review. This condition should be recognized by pediatricians in order not to put patiens throught lengthy, expensive and unnecessary investigation. |