Současné trendy v terapii bolesti u popálených pacientů. Opioidní, neopiodní a nefarmakologické ovlivnění bolesti´
| Title in English | Current trends in pain therapy in burn patients Opioid, non-opioid and non-pharmacological effects on pain |
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| Authors | |
| Year of publication | 2024 |
| Type | Article in Periodical |
| Magazine / Source | Klinická farmakologie a farmacie |
| MU Faculty or unit | |
| Citation | |
| web | http://klinickafarmakologie.cz/artkey/far-202403-0003_soucasne_trendy_v_terapii_bolesti_u_popalenych_pacientu_opioidni_neopioidni_a_nefarmakologicke_ovlivneni_bole.php |
| Doi | http://dx.doi.org/10.36290/far.2024.017 |
| Keywords | pain; burns; opioids; analgesics |
| Description | One of the primary difficulties in treating burn patients lies in efficacious pain management. Pain arising from thermal injury is amalgamated with a multifaceted composition, encompassing acute, neuropathic, inflammatory, and nociceptive traits. Inadequate management of painful stimuli leads to reduced patients' "compliance" and can prolong recovery times with a detrimental impact on the patient's quality of life, given pain's known association with negative perceptions such as fear and anxiety. Opioids are the preferred drug for treating extensive burns. However, administration must consider several crucial factors such as the patient's consciousness state, pain perception, associated diseases and complications, and the surgical treatment plan or hospital stay length, which may exceed five months or longer. The efficiency of opioids significantly declines after repeated or constant administration during this period. In addition, administering opioids results in several adverse effects. Therefore, it is advisable to integrate them with additional drug regimens like ketamine, non-steroidal anti-inflammatory drugs (NSAIDs), paracetamol, pregabalin, anxiolytics, as well as non-pharmacological methods such as psychological support, hypnosis, meditation, aromatherapy, virtual reality, and appropriate rehabilitation. Psychosocial family support plays a crucial role as well. |