Use of chemical dosimetry for comparison of ultrasound and ionising radiation of cavitation
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Physiological Research |
| MU Faculty or unit | |
| Citation | |
| Field | Biophysics |
| Keywords | cavitation; dosimetry; ultrasound; ionising radiation |
| Description | A comparison of the effects of ultrasound (US) produced by US apparatuses in biological systems is one of the basic problems when studying US cavitation effects. A possibility for how to compare these effects are the indirect methods which use quantities characterizing the interaction of ionizing radiation with matter and which also converts these quantities to one common physical quantity. The first method employed a dosimeter composed of 50 % chloroform and 50 % re-distilled water (Taplin dosimeter). The other method used a iodide dosimeter - 0.5 M KI solution. After irradiation or US exposure, chemical changes occurred in both dosimeters, which were proportional to the exposure. The UZD 21 US disintegrator (22 kHz, 50 % power output) was used as a low frequency US source, and the BTL-07 therapeutic device (1 MHz, intensity of 2 W/cm2) was used as a high-frequency US source. For comparison, a 60Co gamma source was applied (gamma-rays 1.17 and 1.33 MeV, 14 PBq). Results have demonstrated that the sonochemical products are generated during exposure in both dosimeters for all apparatuses used. The resulting cavitation effects were recalculated to a gray-equivalent dose based on the sonochemical effects compared to the effects of ionizing radiation from the 60Co source. |