Léčba nemocných s nemalobuněčným plicním karcinomem s přestavbou genu ALK
| Title in English | Treatment of patients with non-small cell lung cancer with ALK rearrangement |
|---|---|
| Authors | |
| Year of publication | 2018 |
| Type | Peer-reviewed scientific article |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| web | https://www.scopus.com/record/display.uri?eid=2-s2.0-85057361024&origin=resultslist&sort=plf-f&src=s&st1=venclicek+o&st2=&sid=dd308ecd0b8e152e45ac46de4197df5e&sot=b&sdt=b&sl=24&s=AUTHOR-NAME%28venclicek+o%29&relpos=0&citeCnt=0&searchTerm= |
| Keywords | Anaplastic lymphom kinase (ALK); Biological therapy; Non small cell lung cancer (NSCLC);Tyrosinkinase inhibitors (TKI) |
| Description | The article presents a brief summary of the basic theoretical knowledge of non-small cell lung cancer harbouring mutation in the anaplastic lymphomkinase (ALK) gene. It also discusses the current possibilities of oncology therapy targeting the ALK mutation - the inhibitors of ALK signaling pathway and current options of their use in the Czech Republic. |