NBQX attenuates relapse of nicotine seeking but not nicotine and methamphetamine self-administration in rats
| Authors | |
|---|---|
| Year of publication | 2021 |
| Type | Article in Periodical |
| Magazine / Source | The World Journal of Biological Psychiatry |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.tandfonline.com/doi/full/10.1080/15622975.2021.1907714 |
| Doi | http://dx.doi.org/10.1080/15622975.2021.1907714 |
| Keywords | AMPA/kainate receptor; Nicotine; Methamphetamine; Self-administration; Relapse |
| Description | Pharmacological manipulations of glutamatergic ionotropic receptors have been suggested as a promising target for addiction treatment. Antagonists of AMPA/kainate receptors were shown to reduce alcohol intake or alcohol-seeking in various animal models. In this study, we evaluated the effect of NBQX, an AMPA/kainate receptor antagonist, on methamphetamine (METH) and nicotine self-administration in rats. |
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