Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2018127
- Období řešení
- 1/2020 - 12/2022
- Investor / Programový rámec / typ projektu
-
Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
- Spolupracující organizace
-
Biotechnologický ústav AV ČR, v.v.i.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies, will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB is a part of the ESFRI project INSTRUCT-ERIC.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 249
2023
-
Asymmetric Hydroxymethylation of Isoindolinones Using Bench-Stable Formaldehyde Surrogates
Rok: 2023, druh: Další prezentace na konferencích
-
Bio-AFM exploits enhanced response of human gingival fibroblasts on TiO2 nanotubular substrates with thin TiO2 coatings
Applied Surface Science Advances, rok: 2023, ročník: 18, vydání: December 2023, DOI
-
Cardiovascular Diseases
Mechanics in Diseased Cells and Tissues, Volume 2 Biomedical Applications, rok: 2023, počet stran: 26 s.
-
Catalytic activity of a new Cd (II) complex in the peroxidation of cyclohexane and the resulting CdO nanoparticles in the removal of Congo red
Applied Organometallic Chemistry, rok: 2023, ročník: 37, vydání: 6, DOI
-
Catalytic mechanism for Renilla-type luciferases
Nature Catalysis, rok: 2023, ročník: 6, vydání: 1, DOI
-
Catechol-O-methyl transferase suppresses cell invasion and interplays with MET signaling in estrogen dependent breast cancer
Scientific Reports, rok: 2023, ročník: 13, vydání: 1, DOI
-
Competing and directing interactions in new phosphoramide/thiophosphoramide structures: energy considerations and evidence for CHMIDLINE HORIZONTAL ELLIPSISHC contacts and aliphatic-aromatic stacking
CrystEngComm, rok: 2023, ročník: 25, vydání: 17, DOI
-
Convergent Assembly of the Tricyclic Labdane Core Enables Synthesis of Diverse Forskolin-like Molecules
Angewandte Chemie International Edition, rok: 2023, ročník: 62, vydání: 1, DOI
-
Copper Phosphinate Complexes as Molecular Precursors for Ethanol Dehydrogenation Catalysts
Inorganic Chemistry, rok: 2023, ročník: 62, vydání: 49, DOI
-
Corynebacterium antarcticum sp. nov., Corynebacterium marambiense sp. nov., Corynebacterium meridianum sp. nov., and Corynebacterium pygosceleis sp. nov., isolated from Adélie penguins (Pygoscelis adeliae)
Systematic and Applied Microbiology, rok: 2023, ročník: 46, vydání: 1, DOI