QUANTITATIVE ESTIMATION OF LEFT VENTRICULAR MYOCARDIAL PERFUSION BASED ON DYNAMIC CT SCANS

Autoři	RIENMUELLER T. BAUMGARTNER C. HANDLER M. MAKARENKO V. OUŘEDNÍČEK Petr KRESTINICH I. M. ZHORZHOLIANI S. T. RIENMUELLER R. BOCKERIA L.
Rok publikování	2013
Druh	Článek v odborném periodiku
Časopis / Zdroj	Biomedical Engineering-Biomedizinische Technik
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
www	http://dx.doi.org/10.1515/bmt-2013-4288
Doi	http://dx.doi.org/10.1515/bmt-2013-4288
Obor	Ostatní lékařské obory
Klíčová slova	Myocardial perfusion; indicator dilution; dynamic CT scans
Popis	Computed tomography (CT) is considered an upcoming technology for the quantitative estimation of myocardial perfusion (MPF). Based on previous results that affirm the feasibility of estimating global MPF using a CT scanner in an animal model, this work evaluates the computation of MPF in patients by comparing two different mathematical approaches based on the indicator dilution method. The first, the so called upslope method, was already used in the previous study, the second uses a deconvolution model which possibly is more suitable in the evaluation of regional MPF measurements. A good correlation between both methods could be found and the quantitative results of both methods correspond well to myocardial perfusion values as described in the literature.