Epidemiology of acute pancreatitis in the Czech Republic – the South Moravian region in 2009-2010
| Autoři | |
|---|---|
| Rok publikování | 2014 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Gastroenterologia Polska |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Ostatní obory vnitřního lékařství |
| Klíčová slova | acute pancreatitis; incidence; idiopathic; biliary etiology; age |
| Popis | Background: Many reports were published about the increasing incidence of acute pancreatitis (AP) over the last few decades. It is probable that AP will remain an important clinical problem in the future. Aim: The aim of this study was to establish incidence, etiology and case fatality of AP in the central part of the South Moravian region of the Czech Republic with the population of 1.3 million. Methods: We recorded and analyzed data of all patients hospitalized with the diagnosis of AP in contributing hospitals of the South Moravian region in the years 2009 and 2010. Results: We analyzed records of the 261 patients diagnosed with AP, the overall incidence in the area was 10,07/100,000 inhabitants/year. Biliary etiology was found in 43.3% of cases, alcoholic in 34.1% and AP was idiopathic in 11.1%. Post- ERCP etiology was found in 5% of cases, drug induced AP in 2.3% and miscellaneous in 4.2%. There were 28 deaths which was 10.7% of all cases. The case fatality of alcoholic and biliary AP was similar (9% and 8% respectively) while other etiologies had more than twofold overall death rate (18.6%). The AP was identified as severe in 45.2% of cases, most of which were of alcoholic origin. The case fatality of the severe AP in the study group was 23.7%. The mean age of the deceased patients was 9 years higher than the overall mean age and we found a significant increasing trend in death rates in the higher age groups. Conclusions: The Czech Republic is the country with biliary predominance in the etiology of AP. Our study showed similar case fatality of both biliary and alcoholic AP, while the overall death rate of the other etiologies was more than twofold. Our results suggest the increasing age to be an important risk factor for mortality in AP. |