Recent Approaches in Tooth Engineering Research

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ŠVANDOVÁ Eva VESELÁ Barbora KŘIVÁNEK Jan HAMPL Aleš MATALOVÁ E.

Rok publikování 2014
Druh Článek v odborném periodiku
Časopis / Zdroj Folia biologica
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Genetika a molekulární biologie
Klíčová slova engineering; tooth; stem cells; culture techniques
Popis Tooth absence and defects caused by various reasons are frequent events in humans. They are not life threatening but may bring about social consequences. Recent dentistry provides solutions in the form of prosthetics or dental implants; however, several complications and distinct limitations favour bioengineering of dental and periodontal structures. At least two types of cells (epithelial and mesenchymal) have to be recombined to produce a new functional tooth. Moreover, the tooth must be vascularized, innervated and properly anchored in the bone. To study these issues, different approaches have been established in both basic and applied research. In this review, recent strategies and techniques of tooth engineering are comprehensively summarized and discussed, particularly regarding manipulation using stem cells.
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