Fibrous Dysplasia Presenting as a Cold Spot in F-18-FLT PET/CT Imaging

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ŘEHÁK Zdeněk BENCSIKOVA Beatrix ZAMBO Iva KAZDA Tomáš

Rok publikování 2016
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Fakulta / Pracoviště MU

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Popis Fibrous dysplasia (FD) is a benign bone lesion in which normal bone marrow is replaced by fibro-osseous tissue. The usual high fluorodeoxyglucose (F-18-FDG) uptake in FD may lead to the misdiagnosis of bone malignancy. Herein, we describe the case of a 42-year old man with histologically verified FD of the pubic bone, which has been subsequently examined during follow-up for rectal cancer, using both F-18-FDG and fluorothymidine (F-18-FLT) PET/CT imaging. The FD lesion was characterized by a high uptake of F-18-FDG (hot spot) but very low uptake of F-18-FLT (cold spot) as compared with the contralateral unaffected pubic bone.

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