Antibacterial activity of AgNPs-TiO2 nanotubes: influence of different nanoparticle stabilizers

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BILEK Ondrej FIALOVA Tatiana OTAHAL Alexandr ADAM Vojtech SMERKOVA Kristyna FOHLEROVÁ Zdenka

Rok publikování 2020
Druh Článek v odborném periodiku
Časopis / Zdroj RSC Advances
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra07305a
Doi http://dx.doi.org/10.1039/d0ra07305a
Klíčová slova AgNPs-TiO2 nanotubes; nanoparticle stabilizers
Popis Enhanced antibacterial properties of nanomaterials such as TiO2 nanotubes (TNTs) and silver nanoparticles (AgNPs) have attracted much attention in biomedicine and industry. The antibacterial properties of nanoparticles depend, among others, on the functionalization layer of the nanoparticles. However, the more complex information about the influence of different functionalization layers on antibacterial properties of nanoparticle decorated surfaces is still missing. Here we show the array of similar to 50 nm diameter TNTs decorated with similar to 50 nm AgNPs having different functionalization layers such as polyvinylpyrrolidone, branched polyethyleneimine, citrate, lipoic acid, and polyethylene glycol. To assess the antibacterial properties, the viability of Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) has been assessed. Our results showed that the functional layer of nanoparticles plays an important role in antibacterial properties and the synergistic effect such nanoparticles and TiO2 nanotubes have had different effects on adhesion and viability of G(-) and G(+) bacteria. These findings could help researchers to optimally design any surfaces to be used as an antibacterial including the implantable titanium biomaterials.

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