Dynamics of clinical response to paroxetine in coherence with CYP 2D6 metabolic status during long-term therapy of depressive disorder.
| Autoři | |
|---|---|
| Rok publikování | 2001 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | South African Journal of Science |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Psychiatrie, sexuologie |
| Klíčová slova | Genetic polymorphism; cytochrome P450; SSRI; psychiatry; sexual disorder |
| Popis | Long-term therapy with SSRI antidepressants can evoke adverse effects including sexual disorders which may be more pronounced in patients with decreased activity of CYP 2D6, either given by the defect of the enzyme expression or evoked by previous treatment with enzyme inhibitors. |
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