Methods available for collaborative research

First Department of Neurology, St. Anne´s University Hospital

  • Invasive EEG (stereo EEG), sampling frequency 25 kHz
  • HD-EEG 128-channel system
  • rTMS with noninvasive neuronavigation

Contact: Milan Brázdil,

Multimodal and Functional Imaging Laboratory - MAFIL, CEITEC, Masaryk University

  • Two human whole-body MR scanners with efficient gradient system (up to 80 mT/m, 200 T/m/s) equipped with various coils, one scanner with multinuclear support (Phosphor/Hydrogen head and flexible coils available), open system for sequence development and installation of user sequences
  • Equipment for fMRI stimulation and response - LCD screens, buttons, tablet, eye tracking system, physiological recordings (ECG, breathing, skin conductance, ...)
  • High density EEG system with 256 channels, MR compatible, possibility of tDCS/tACS stimulation
  • EEG with 32 channels, MR compatible, rTMS compatible
  • rTMS system with frameless stereotactic navigation (noninvasive neuronavigation based on MR images)
  • shielded electrophysiological labs with equipment for stimulation, possibility to combine TMS, EEG, physiological recording and eye-tracking

Contact: Michal Mikl,,

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First Department of Pathology, St. Anne´s University Hospital

  • Histopathology, standard and special staining methods
  • Immunohistochemistry and immunofluorescence
  • Fluorescent in situ hybridization

 Contact: Marketa Hermanová,

Department of Neurology, University Hospital Brno

  • Contact Heat Evoked Potentials
  • Quantitative Sensory Testing (utilizing DFNS protocol)
  • Skin biopsy (intraepidermal nerve fiber density)
  • Corneal Confocal Microscopy (corneal nerve fibre density).

Contact: Josef Bednařík,

Department of Physiology, Faculty of Medicine, Masaryk University

  • Whole cell patch clamp
  • Multielectrode array 

Contact: Markéta Bébarová,

Central animal facility of the Faculty of Medicine

  • Operant IV self-administration of addictive substances
  • Alcohol drinking model
  • Behavioral testing in mice and rats (locomotion, social interactions, memory, motor impairment, etc.)

Contact: Jana Ruda-Kucerova,

Department of Anatomy, Research Group: Cellular and Molecular Neurobiology, Faculty of Medicine, Masaryk University

  • Experimental models of neuropathic pain based on spinal or trigeminal nerve injury
  • Behavioural tests: mechanical and thermal hypersensitivity
  • In situ proteomics and image analysis
  • Ex vivo electrophysiological measurement of skin-nerve preparation

Contact: Marek Joukal,; Petr Dubový,

More information at:

Department of Biomedical Engineering, International Clinical Research Center - St. Anne's University Hospital & Institute of Scientific Instruments, The Czech Academy of Sciences, Brno

  • High-frequency and high-dynamic signal acquisition
  • Shielded room - Faraday cages
  • Automated signal processing
  • Machine learning and AI utilization
  • Archiving and organization of extensive data

Contact: Pavel Jurák, & Jan Cimbálník,

Institute of Scientific Instruments of the Czech Academy of Science

  • Magnetic resonance 9.4T / 30cm
  • Objects: in vivo mouse/rat/rabbit (anesthesized, monitored), ex vivo organs, in vitro samples
  • Techniques: anatomic T1w, T2w, T2*w imaging, perfusion (DCE, DSC, ASL), diffusion (DW-MRI, DTI, DKI), relaxometry (T1, T2, T2*), spectroscopy (single-voxel PRESS/STEAM); in-magnet focused ultrasound
  • Nuclei: 1H, 13C, 19F, 23Na, 31P
  • Support for: experiment design, animal-use project preparation
  • Animal housing

Contact: Zenon Starčuk jr.,

Department of Histology and Embryology, Faculty of Medicine, Masaryk University

  • Generation of human induced pluripotent stem cell lines for disease modelling
  • shRNA approach for gene downregulation, vector design and cloning
  • Generation of CRISPR/Cas9 knockouts
  • Production of lentiviral particles
  • Retinal organoids derived from human induced pluripotent stem cells
  • Generation of vectors for manipulation with microRNA expression

Contact: Tomáš Bárta,

More information at:


  • Modeling neuronal development and disease in vitro using human induced pluripotent stem cells
  • iPSC generation from patients' PBMCs
  • differentiation towards neural stem cells, mature neurons and 3D cerebral organoids
  • CRISPR/Cas9 Knock-in and Knock/out

Contact: Dáša Bohačiaková,

More information at:

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