An epigenetic view of anxiety disorders, one cell type at a time
A recent publication by Ingram et al. revealed the importance of cellular precision in psychiatric epigenetics.
Using cellular deconvolution, the authors showed that anxiety is associated with cell type-specific DNA methylation signatures reflecting stress, inflammation, and accelerated aging. T
hese findings have critical implications for neuroscience studies aiming to bridge the gap between the peripheral epigenome and brain function.
Keywords: DNA methylation; aging; cell type-specific analysis; genetics; methylome-wide association analysis (MWAS); psychiatric disease.
