Instructions for students

Lectures - presentations

1

16/9/08

Pathological physiology as integrating medical speciality. Common disease causations. Aetiology and pathogenesis.

Prof. Vašků

2

23/ 9/08

Pathophisiology of malignant transformation.      0809

Assoc. Prof. Kaňková

3

30/9/08

Inflammation. Acute phase reaction. Cytokines network. Chemokines.

Assoc. Prof. Kaňková

4

7/10/08

Regeneration. Wound healing.                               0809

Assoc. Prof. Kaňková

5

14/10/08

Volume and pressure overload of heart, systolic and diastolic dysfunction. Shock and heart failure.

Prof. Vašků

6

21/10/08

Ischemic heart disease, myocardial infarction, arrhythmias: pathogenesis and selected clinical aspects.

Assoc. Prof. Kaňková

7

28/10/08

Bank holiday

 

8

4/11/08

Lipids0809

Assoc. Prof. Kaňková

9

11/11/08

General adaptation syndrome.

Prof. Vašků

10

18/11/08

Pathophysiology of gas exchange in the lungs and regulation of ventilation.

Prof. Izakovičová Hollá

11

25/11/08

Lung diseases.

Prof. Izakovičová Hollá

12

2/12/08

Kidney as a regulatory organ. Perfusion of kidney.

Prof. Vašků

13

9/12/08

Acute and chronic renal failure.

Prof. Izakovičová Hollá

14

16/12/08

Glomerular and tubular diseases.

Prof. Izakovičová Hollá

 

1

17. 2. 2009

Pathophysiology of gastrointestinal tract.

Prof. Vašků

2

24. 2. 2009

Common cell reaction to injury. Apoptosis. Necrosis.

Prof. Vašků

3

3. 3. 2009

Pathophysiology of calcium homeostasis

Prof. Vašků

4

10. 3. 2009

Diabates mellitus

Assoc. prof. Kaňková

5

17. 3. 2009

Pathophysiology of allergic states.

Prof. Izakovičová Hollá

6

24. 3. 2009

Pathophysiology of selected autoimmune disorders.

Prof. Izakovičová Hollá

7

31. 3. 2009

Pathophysiology of bones and muscles.

Prof. Vašků

8

7. 4. 2009

General pathophysiology of salt and water metabolism.

Prof. Vašků

9

14. 4. 2009

Disorders of intravascular volume and tonicity.

Prof. Vašků

10

21 .4. 2009

Pathophysiology of endocrine system

Prof. Vašků

11

28. 4. 2009

Pathophysiology of food intake.

Assoc. Prof. Kaňková

12

5. 5. 2009

Pathophysiology of neural system

Prof. Vašků

13

12. 5. 2009

Pathophysiology of blood forming tissue. Pathophysiology of blood clotting.

Prof. Vašků

14

19. 5. 2009

DNA diagnostics in complex diseases.

Prof. Vašků

15

26. 5. 2009

Pharmacogenomics and gene therapy

Prof. Vašků

 

Practical Trainings

Autumn 2008

1.

17/9

18/9

Ethical issues in the use of animals in research. Safety in the laboratory. Studies on laboratory animals. Preparation of animals for experiments. Surgical technique basic course.

 

2.

24/9

25/9

Pathophysiology of blood.

3.

1/10

2/10

Statistical evaluation of experimental data I.

 

4.

8/10

9/10

Radiation damage of blood forming tissues I.

 

5.

15/10

16/10

Radiation damage of blood forming tissues II.

 

6.

22/10

23/10

Ambulatory monitoring of blood pressure. Blood pressure and heart rate changes associated with orthostatic changes, isometric muscle tension and light physical exercise.

 

7.

29/10

30/10

Examination of the lung function in man. Pathophysiology of respiratory system.

8.

5/11

6/11

Atherosclerosis, dopplerometry.

 

9.

12/11

13/11

Pathophysiology of heart

10.

19/11

20/11

 Electrocardiography  and arrhythmias in the animal model  Model of renal ischemia in the rat.

 

11.

26/11

27/11

Secondary hypertension (seminar), exp. induced renal ischemia -quantification of renin expression

 

12.

3/12

4/12

Exp. induced acute renal insufficiency in lab. animal - measurement of GFR based on kinetics of renal inulin excretion.

 

13.

10/12

11/12

Exp. induced renal failure - peritoneal dialysis in lab. animal

 

14.

17/12

18/12

Exp. induced atherosclerosis in lab. animal - assessment of vessel remodelation

 

Practicals spring 2009 - presentations

week

date

topic

1

18, 19/2

Exp. induced peptic ulcer – quantification of gastric juice secretion in lab. animal

 [dr. Michal Jurajda, PhD., Lukáš Pácal, MA, PhD.]

2

25, 26/2

Exp. induced vein thrombosis in lab. animal

[Michal Masařík, MA, PhD., Lukáš Pácal, MA, PhD.]

3

4, 5/3

Pathophysiology of acid-base balance disorders (seminar)

[dr. Kateřina Kaňková, PhD., Lukáš Pácal, MA, PhD.]

4

11, 12/3

Exp. induced effect of selected pharmacologically active substances on microcirculation in lab. animal

[dr. Michal Jurajda, PhD., Michal Masařík, MA, PhD.]

5

18, 19/3

Use of enzyme (and other) markers in diagnostics of selected pathophysiological states – evaluation of LDH isoenzymes

[Lukáš Pácal, MA, PhD., dr. Michal Jurajda, PhD.]

6

25, 26/3

Exp. induced diabetes mellitus – diagnostic by glucose tolerance test

[Lukáš Pácal, MA, PhD., dr. Kateřina Kaňková, PhD.]

7

1, 2/4

Genetic susceptibility to disease – monogenic vs. complex disease (tutorial)

[dr. Kateřina Kaňková, PhD., dr. Michal Jurajda, PhD.]

8

8, 9/4

Principles of DNA diagnostics – detection of I/D polymorphism in the ACE gene by PCR, electrophoresis of the PCR products

[dr. Michal Jurajda, PhD., Michal Masařík, MA, PhD.]

9

15, 16/4

Overview  of molecular biology exp. methods used in pathophysiology (seminar & demonstration of selected lab. methods)

 [dr. Kateřina Kaňková, PhD., Michal Masařík, MA, PhD.]

10

22, 23/4

Exp. induced anaphylactic response in lab. animal (part 1)

[Michal Masařík, MA, PhD., dr. Kateřina Kaňková, PhD.]

11

29, 30/4

Exp. induced anaphylactic response in lab. animal (part 2)

[Michal Masařík, MA, PhD., dr. Kateřina Kaňková, PhD.]

12

6, 7/5

Food intake disorders (seminar) – assessment of the nutritional status and energy metabolism (BodyStat - demonstration)

[Michal Masařík, MA, PhD., Lukáš Pácal, MA, PhD.]

13

13, 14/5

Exp. induced haemolytic, hepatotoxic and obstruction jaundice in lab. animal

[Lukáš Pácal, MA, PhD., Michal Masařík, MA, PhD.]

14

20, 21/5

Statistical evaluation of experiments (advanced methods), practical analysis of exp. data (application of stat. software)

[dr. Michal Jurajda, PhD., dr. Kateřina Kaňková, PhD.]

15

27, 28/5

Topic reserved + tests, revision, credits

[dr. Kateřina Kaňková, PhD., dr. Michal Jurajda, PhD.]

 

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