Mgr. Jiří Sedmík, Ph.D.
Research specialist, Dáša Bohačiaková Research Group: Neurobiology of the Development and Disease
Total number of publications: 16
2024
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Generation of the Human iPSC Line from Spontaneous Late-Onset Alzheimer's Disease Patient with ApoE3/3 Genotype and Sex-, Age-, and ApoE-Matched Healthy Control
Stem cell research, year: 2024, volume: 74, edition: February 2024, DOI
2023
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Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development
CELL REPORTS, year: 2023, volume: 42, edition: 11, DOI
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Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
Molecular Neurodegeneration, year: 2023, volume: 18, edition: 1, DOI
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Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration
MOLECULAR ONCOLOGY, year: 2023, volume: 17, edition: 4, DOI
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Studying mechanisms of Alzheimer’s disease development using cerebral organoids
Year: 2023, type: Appeared in Conference without Proceedings
2022
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ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations
RNA, year: 2022, volume: 28, edition: 10, DOI
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Cerebral organoids in disease modeling.
Year: 2022, type: Conference abstract
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Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids
Stem Cell Reviews and Reports, year: 2022, volume: 18, edition: 2, DOI
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Using a human pluripotent stem cell-based model to study the Alzheimer's disease pathogenesis in vitro
Year: 2022, type: Conference abstract
2021
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ADAR RNA Modifications, the Epitranscriptome and Innate Immunity
Trends in Biochemical Sciences, year: 2021, volume: 46, edition: 9, DOI