Mgr. Jan Raška, Ph.D.

2023

• Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

  NEMERGUT Michal MARQUES Sérgio Manuel UHRÍK Lukáš VÁŇOVÁ Tereza NEZVEDOVÁ Markéta GADARA Darshak Chandulal JHA Durga TULIS Jan NOVÁKOVÁ Veronika PLANAS IGLESIAS Joan KUNKA Antonín LEGRAND Anthony Thomas P HŘÍBKOVÁ Hana POSPÍŠILOVÁ Veronika SEDMÍK Jiří RAŠKA Jan PROKOP Zbyněk DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk HERNYCHOVÁ Lenka BEDNÁŘ David MAREK Martin

  Article in Periodical

  Molecular Neurodegeneration, year: 2023, volume: 2023, edition: 18:38, DOI

• Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration

  FEDOROVÁ Veronika POSPÍŠILOVÁ Veronika VÁŇOVÁ Tereza AMRUZ ČERNÁ Kateřina ABAFFY Pavel SEDMÍK Jiří RAŠKA Jan VOCHYÁNOVÁ Simona MATŮŠOVÁ Zuzana HOUSEROVÁ Jana VALIHRACH Lukáš HODNÝ Zdeněk BOHAČIAKOVÁ Dáša

  Article in Periodical

  MOLECULAR ONCOLOGY, year: 2023, volume: 17, edition: 4, DOI

• Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits

  NEZVEDOVÁ Markéta JHA Durga VÁŇOVÁ Tereza GADARA Darshak Chandulal KLÍMOVÁ Hana RAŠKA Jan OPÁLKA Lukáš BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk

  Article in Periodical

  ANALYTICAL CHEMISTRY, year: 2023

2022

• Cerebral organoids in disease modeling.

  SEDMÍK Jiří VÁŇOVÁ Tereza RAŠKA Jan AMRUZ ČERNÁ Kateřina POSPÍŠILOVÁ Veronika FEDOROVÁ Veronika FOJTÍK Petr VOCHYÁNOVÁ Simona KLÍMOVÁ Hana PLEŠINGROVÁ Klára TAUŠ Petr PLEVOVÁ Karla NEZVEDOVÁ Markéta SPÁČIL Zdeněk CAPANDOVÁ Michaela ORVISKÁ Petra BENEŠOVÁ Z. ABAFY P. VALIHRACH L. HOUSEROVÁ Jana

  Conference abstract

  Year: 2022, type: Conference abstract

• Endocrine-disrupting chemicals affect Sertoli TM4 cell functionality through dysregulation of gap junctional intercellular communication in vitro

  YAWER Affiefa SYCHROVÁ Eliška RAŠKA Jan BABICA Pavel SOVADINOVÁ Iva

  Article in Periodical

  Food and Chemical Toxicology, year: 2022, volume: 164, edition: June 2022, DOI

• Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids

  BARÁK Martin FEDOROVÁ Veronika POSPÍŠILOVÁ Veronika RAŠKA Jan VOCHYÁNOVÁ Simona SEDMÍK Jiří HŘÍBKOVÁ Hana KLÍMOVÁ Hana VÁŇOVÁ Tereza BOHAČIAKOVÁ Dáša

  Article in Periodical

  Stem Cell Reviews and Reports, year: 2022, volume: 18, edition: 2, DOI

• Pathological SORLA protein variant in Alzheimer's disease development

  PLEŠINGROVÁ Klára RAŠKA Jan BOHAČIAKOVÁ Dáša POSPÍŠILOVÁ Veronika

  Conference abstract

  Year: 2022, type: Conference abstract

• Single cerebral organoid mass spectrometry analysis: Towards neurodegenerative diseases

  NEZVEDOVÁ Markéta VÁŇOVÁ Tereza RAŠKA Jan BOHAČIAKOVÁ Dáša SPÁČIL Zdeněk

  Conference abstract

  Year: 2022, type: Conference abstract

2021

• Generation of six human iPSC lines from patients with a familial Alzheimer's disease (n=3) and sex- and age-matched healthy controls (n=3)

  RAŠKA Jan HŘÍBKOVÁ Hana KLÍMOVÁ Hana FEDOROVÁ Veronika BARÁK Martin BÁRTA Tomáš POSPÍŠILOVÁ Veronika VOCHYÁNOVÁ Simona VÁŇOVÁ Tereza BOHAČIAKOVÁ Dáša

  Article in Periodical

  Stem cell research, year: 2021, volume: 53, edition: May 2021, DOI

• Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls

  RAŠKA Jan KLÍMOVÁ Hana SHEARDOVÁ Kateřina FEDOROVÁ Veronika HŘÍBKOVÁ Hana POSPÍŠILOVÁ Veronika VOCHYÁNOVÁ Simona VÁŇOVÁ Tereza BOHAČIAKOVÁ Dáša

  Article in Periodical

  Stem cell research, year: 2021, volume: 53, edition: May 2021, DOI