Interakce účinků extáze, metamfetaminu a kanabinoidů v animálních modelech
| Title in English | Interactions of the ecstasy, methamphetamine and cannabinoids effects in animal models |
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| Authors | |
| Year of publication | 2006 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Repeated administration of MDMA elicited in mice in the open field test both development and expression of sensitization. Repeated pre-treatment by CB1 receptor agonist led to cross-sensitization to the MDMA challenge dose and, in contrary, repeated administration of CB1 receptor antagonist+MDMA suppressed this phenomenon. We did not confirm our hypothesis, that repeated administration of MDMA would sensitise to antiaggressive effects in the mice model of agonistic behaviour. |
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