ZKUŠENOSTI S AUGMENTACÍ KLOZAPINU DEPOTNÍMI ANTIPSYCHOTIKY

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Title in English EXPERIENCE WITH CLOZAPINE AUGMENTATION WITH DEPOT ANTIPSYCHOTICS
Authors

KOTOLOVÁ Hana NOVÁKOVÁ Martina NOVÁKOVÁ Eliška HAMMER Tomáš MAYEROVÁ Michaela USTOHAL Libor

Year of publication 2023
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Pharmacy

Citation
Description The poster presents a summary of previous experience with the administration of a combination of clozapine and LAI APs in patients hospitalized at the Psychiatric Clinic of the FN Brno in 2016–2020. A total of 15 patients who met the entry criteria for this comparison were included in the retrospective analysis. The poster mainly evaluates the length of the previous therapy, the representation of individual depot antipsychotics within the augmentation approach, the achievement of remission or relapse of the disease within the augmentation, and the recorded side effects. The results suggest that patients nonadherent and resistant to clozapine therapy could benefit from this treatment, although the amount of clinical data is currently low. Augmentation of clozapine LAI APs should be individualized, based on the sufficient professional experience of the attending physician.

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