Changes of CYP2D6 acitivity in rats after drugs of abuse medication
| Authors | |
|---|---|
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Homeostasis |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | CYP2D6; drugs of abuse; metabolism; inhibition |
| Description | The aim of the study was to establish the influence of long term medication of metamphetamine on the cytoshrome P450 2D1/6 activity in rats in "i.v. self-administration" model.Insignificant decrease in the enzyme activity was recorded. |
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