Non-Watson-Crick Base Pairing and Hydration in RNA motifs: Molecular Dynamics of 5S rRNA Loop E

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Authors

RÉBLOVÁ Kamila ŠPAČKOVÁ Naděžda KOČA Jaroslav LEONTIS Neocles ŠPONER Jiří

Year of publication 2003
Type Article in Proceedings
Conference Journal of Biomolecular Structure and Dynamics
MU Faculty or unit

Faculty of Science

Citation
Field Biophysics
Keywords molecular dynamics simulations; Loop E motifs; non-Watson-Crick base pairs; ordered hydration; 5S rRNA.
Description Internal loops are common elements of RNA secondary structure. They often form binding sites for metals, proteins and other RNAs. To under-stand the effects of internal loops on RNA structure and function, we have carried out molecular dynamics simula-tions on two RNA Eloop motifs
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