Vliv lateralizace fokálních mozkových lézí na stav imunitního systému u pacientů po těžkém poranění mozku

Title in English The influence of lateralization of brain lesions on an immune system status in the patients after severe brain injury
Authors

MRLIAN Andrej SMRČKA Martin KLABUSAY Martin

Year of publication 2006
Type Article in Proceedings
Conference Kuncův memoriál 2006
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords severe brain injuries; immune system disorders; lateralization; extracranial inflammatory complications
Description 1, Severe head injuries definitely change cellular as well as humoral part of immune system. Extracranial complications caused by immunity disorders worsen the prognosis. 2, Comparing immune system disorders with various site of brain damage a relevant difference has been disclosed, T– Lymphocytes (CD3+, CD4+) have been lower by the left located damages and their gradual normalization was slower. 3, Various localization of primary as well as secondary brain damage affects immune system in the patients after severe brain injury. The deeper decrease in left located injury group is succeeded by higher occurrence of extra cranial complications and finally it has led to a higher mortality in this group
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