Novinky v diagnostice a léčbě neuroblastomu.

Title in English Advances in neuroblastoma diagnostics and treatment.
Authors

MAZÁNEK Pavel BAJČIOVÁ Viera ŠTĚRBA Jaroslav KUGLÍK Petr VESELSKÁ Renata

Year of publication 2008
Type Article in Periodical
Magazine / Source Onkológia
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.solen.sk
Field Oncology and hematology
Keywords neuroblastoma pediatric oncology new terapie antiangiogenic therapy metronomic chemotherapy COMBAT genetics of childhood cancer
Description Neruoblastoma is the most common extracranial solid tumor of a childhood. Neuroblastoma is well known for ist variability in clinical behavioral and distinct biological features. In a history of pediatric oncology it is a first disease, where the biological marker ( NMYC amplification) was used for a prospective therapeutical randomisation. Current research is focused on detection of a new biological prognostic markers in neuroblstoma and implementation af a new therapeutical apporoaches into a clinical practise ( eg. antiangiogenic therapies, metronomic chemotherapy, biotherapy, immunotherapy.)
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