Project information
Characterization of the RAD51 role in TERRA recruitment to telomere

Project Identification
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Medicine

Telomeric repeat containing RNA (TERRA) was revealed to be recruited to telomeres by RAD51 protein by the mechanism resembling strand-invasion and homology-search mechanism utilized in homology directed DNA repair (HDR). However, detailed mechanism of TERRA recruitment remains uncovered. We would like to focus on biochemical characterization of RAD51-TERRA interaction and regulation of TERRA recruitment.

You are running an old browser version. We recommend updating your browser to its latest version.

More info