Chronobiologic Reference Values for Blood Pressure during Pregnancy
| Authors | |
|---|---|
| Year of publication | 2023 |
| Type | Article in Periodical |
| Magazine / Source | World heart journal |
| MU Faculty or unit | |
| Citation | |
| Web | https://novapublishers.com/shop/chronobiologic-reference-values-for-blood-pressure-during-pregnancy/ |
| Keywords | blood pressure; circadian rhythm; gestation; pregnancy; reference values |
| Description | Changes in blood pressure (BP) during the course of pregnancy are revisited based on ambulatory monitoring (ABPM) from 223 pregnant women who contributed 362 records of around-the-clock measurements covering 2 days. Retrospectively, data from women with uncomplicated pregnancies were used to derive time-specified reference values. Circadian rhythm characteristics were also compared between pregnancies complicated by gestational hypertension (G-MH), MESOR-Hypertension (MH) or pre-eclampsia (PE) and uncomplicated (healthy) pregnancies. In clinical health, blood pressure decreases during the second trimester of pregnancy before increasing again to reach pre-pregnancy values at term. The rhythm-adjusted average (MESOR) of systolic BP is elevated in G-MH, MH, and PE, even before these conditions were clinically diagnosed. Chronobiologically-interpreted ABPM in pregnancy can identify complications early, and prompt the timely institution of countermeasures when needed. |