Anxiogenic-like effect of ecstasy in mice on conflict social interactions


ŠULCOVÁ Alexandra LANDA Leoš ŠLAIS Karel

Year of publication 2006
Type Article in Proceedings
Conference Final programme and book abstracts - International Anxiety Disorders Conference 2006
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords anxiety - ecstasy - social interaction - mice
Description The most significant changes measured in timid singly-housed male mice on paired interation with non-aggressive group-housed partners after acutely given ecstasy were in increase of defensive-escape behaviour and decrease of sociable activities (just the highest dose stimulated significantly walking), suggesting anxiogenic-like drug effects.
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