Neparaneoplastická limbická encefalitida s pozitivitou anit-LGI1 protilátek

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Title in English	Non-paraneoplastic limbic encephalitis with positivity of anti-LGI1 antibodies
Authors	DOLEŽALOVÁ Irena KUBA Robert MUSILOVÁ Klára KAŠPÁREK Tomáš BRÁZDIL Milan REKTOR Ivan
Year of publication	2012
Type	Article in Periodical
Magazine / Source	Neurologie pro praxi
MU Faculty or unit	Central European Institute of Technology
Citation
Web	http://www.neurologiepropraxi.cz/savepdfs/neu/2012/04/11.pdf
Field	Neurology, neurosurgery, neurosciences
Keywords	limbic encephalitis; paraneoplastic limbic encephalitis; non-paraneoplastic limbic encephalitis; anti-LGI1 antibodies
Description	Limbic encephalitis (LE) is a condition affecting the limbic system that typically presents with memory disorders, with recent memory being most affected; concurrently, epileptic seizures and psychiatric symptoms can occur. Paraneoplastic limbic encephalitis (PLE) and non-paraneoplastic limbic encephalitis (NLE) are distinguished. Recently, an association of NLE with anti-LGI1 antibodies has been described. We report a case of a 45-year-old female patient with LE and positivity of anti-LGI1 antibodies. The differential diagnosis and treatment of this disease are also discussed.
Related projects:	CEITEC - Central European Institute of Technology