Characterization of the complete nucleotide sequences of IMP-4-encoding plasmids, belonging to diverse Inc families, recovered from Enterobacteriaceae of wildlife origin

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Authors	DOLEJSKÁ Monika PAPAGIANNITSIS Costas C MEDVECKÝ Matej DAVIDOVÁ GERŽOVÁ Lenka VALCEK Adam
Year of publication	2018
Type	Article in Periodical
Magazine / Source	Antimicrobial Agents and Chemotherapy
MU Faculty or unit	Faculty of Science
Citation
Web	Full Text
Doi	http://dx.doi.org/10.1128/AAC.02434-17
Keywords	IncM; IncI1; IncF; IncX5_2; Enterobacter aerogenes; Escherichia coli; Proteus mirabilis; Proteus penneri; In809; In1460
Description	The complete nucleotide sequences of six IMP-4-encoding plasmids recovered from Enterobacteriaceae isolates of wildlife origin were characterized. Sequencing data showed that plasmids of different incompatibility groups (IncM, IncI1, IncF, and nontypeable [including an IncX5_2 and two pPrY2001-like]) carried the blaIMP-4-carrying integrons In809 or In1460. Most of the plasmids carried an mph(A) region, and chrA-like, aac(3)-IId, and blaTEM-1b genes. Finally, plasmid analysis revealed the involvement of two different IS26- and Tn1696-associated mechanisms in the mobilization of IMP-4-encoding integrons.
Related projects:	CEITEC 2020