In silico prediction of the effects of ethanol on cardiac cellular electrophysiology and reentrant arrhythmias

Authors

SUTANTO Henry BÉBAROVÁ Markéta DOBREV Dobromir VOLDERS Paul HEIJMAN Jordi

Year of publication 2019
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Our simulations suggest that ethanol has concentration-­dependent electrophysiological effects that differ between atria and ventricles, and in the absence or presence of AF-­related remodeling. Low concentrations of ethanol could have anti-­AF effects whereas moderate-­ and high-­concentrations may promote AF. These findings facilitate a better understanding of the complex effects of alcohol consumption on cardiac electrophysiology.
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