Cost-effectiveness analysis of isavuconazole for the treatment of invasive aspergillosis in the Czech Republic

Authors

DECKER Barbora MLČOCH Tomáš DOLEŽAL Tomáš CHARBONNEAU Claudie SUNG Anita H. VOTHOVÁ Petra MAZAN Pavol BILLOVÁ Sabina

Year of publication 2018
Type Conference abstract
Citation
Description Over a lifetime horizon, isavuconazole yields additional 0.30 QALYs (7.80 vs. 7.50) at the additional total cost of €3059 (€18,664 vs. €15,605) compared with SoC, with the incremental cost-effectiveness ratio of €10,251 per QALY. PSA showed that probability of isavuconazole to be cost-effective is 75% at the WTP threshold. OWSA and SA confirmed the robustness of the base-case result while the most influential parameters were mortality and prevalence of mucormycosis.

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