Štúdium interakcií orto-substituovaných anilidov 2- / 3- / 4-trifluórmetylškoricových kyselín

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Title in English Investigation of ortho-substituted 2-/3-/4-trifluoromethyl cinnamanilides interactions
Authors

VRÁBLOVÁ Lucia PINDJAKOVÁ Dominika STRHÁRSKY Tomáš GONĚC Tomáš KOS Jiří JAMPÍLEK Josef

Year of publication 2022
Type Conference abstract
MU Faculty or unit

Faculty of Pharmacy

Citation
Description Series of trifluormethylcinnamic acid carboxanilides substituted in ortho position with Cl, F and CF3 was synthesized. Log k, log D and log P values were determined using RP-HPLC. Experimentally obtained values were compared with values predicted using programs with various computing algorithms.

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