Vztah mezi EM a PM CYP 2D6 ve výskytu sexuálních dysfunkcí

Title in English The relation between EM and PM CYP 2D6 in sexual dysfunction
Authors

ŽOURKOVÁ Alexandra HADAŠOVÁ Eva ROBEŠ Miroslav

Year of publication 2001
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords sexual dysfunctions; paroxetine; CYP 2D6; poor metabolizer; extenzive metabolizer
Description The paper deals with th incidence of sexual dysfunction in treatment by paroxetine depending on CYP 2D6 activity. The group of 20 patients included 14 with sexual dysfunction. The statistic comparison (by the Mann-Whitney test) of ASEX UKU and SFM/SFŽ scale items revealed a statistic significant women with recuded CYP 2D6 metabolic capacity in the lubrical on, sexual desire, and self-evaluation items.
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