Vedlejší účinky léčby paroxetinem v závislosti na aktivitě CYP 2D6
| Title in English | The relation of side-effects of treatment by paroxetine to CYP 2D6 activity |
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| Authors | |
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | side effects; paroxetine; CYP 2D6; poor metabolizer; extensive metabolizer |
| Description | The paper is a comparison of the incidence of side effects of treatment by paroxetine in a group of 20 patients as evaluated according to the UKU scale, between patients with the CYP 2D6 phenotype conversion and those in whom the conversion wat not observed. A statistically significance (the chi quadrate test), was found only in association with sexual dysfunction where bad metabolisers were worse off. |
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