Zhodnocení dosavadních zkušeností s dynamikou aktivity CYP2D6
| Title in English | Evaluation of the current experience with the dynamics of CYP2D6 activity |
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| Authors | |
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | Genetic polymorphism; CYP2D6; psychiatry; enzyme inhibition; |
| Description | The study followed the dynamics of the metabolic capacity of CYP2D6 during the 28-day treatment with various psychotropic drugs. It was confirmed that the psychopharmacotherapy may change the CYP2D6 phenotype from the extensive (EM) to the poor (PM) metabolic phenotype. |
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