The assessment of cardioprotective effect of dexrazoxane (ICRF-187) againts late antrhracycline cardiotoxicity in patients treated for childhood cancer
| Title in English | The assessment of cardioprotective effect of dexrazoxane (ICRF-187) against late anthracycline cardiotoxicity in patients treated for childhood cancer. |
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| Authors | |
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | European Journal of Echocardiography |
| MU Faculty or unit | |
| Citation | |
| Description | Clinical cardiotoxicity was found in 4 pts (5%) from group II. After exclusion of these patients wd have not found any difference in rest EF among groups. MPI was worsened in both groups in the compařrison to the controls (p-0,01) and IRT was prolonged in group II (p-0,05)). The increment in EF to dynamic stress was similar in pts and controls (12% group I,16% group II, 18% controls). On the contrary, debulamine stress revealed in 63% of cases the pathological response in patients. An inadequate response of MPI and ESS was present in pts withouuuut cardioprotection. |