Význam CYP2D6 v terapii SSRI
| Title in English | The role CYP2D6 in the treatment with SSRIs |
|---|---|
| Authors | |
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Česká a Slovenská Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | SSRIs;Cytochrome P4502D6; metabolic phenotype; extensive metaboliser; poor metaboliser |
| Description | SSRIs are potent inhibitors of the CYP2D6 activity and that fact may lead to the chahges of metabolic phenotype which may not correspond to metabolic genotype. The result is a great variability in tolerance and efficaccy of SSRIs therapy. |
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