Lipozomální lékové formy pro topické využití
| Title in English | Liposomal drug formulations for topical use |
|---|---|
| Authors | |
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Remedia |
| MU Faculty or unit | |
| Citation | |
| Keywords | liposomes; niosomes; topical administration; heparin; ketoprofen |
| Description | Vesicular drug dosage forms like liposomes and niosomes ment a substantial progress in medical disciplines utilizing topical application. In the transdermal therapeutic systems (TTS) there are utilized also proliposomes and proniosomes. They cross the skin via transcellular and intercellular pathways, but also through skin appendages such as hair follicles, sebaceous glands and eccrine sweat ducts. Liposomal forms increase the drug potency to penetrate into the Stratum corneum (“enhancement") and prolonge retention (accumulation) of the drug in this layer. Viotromb Spray/Gel and Prontoflex 10% were described as examples for utilisation of liposomes and their membrane components in the topical drug therapy. |