Je humorální aktivace u srdečního selhání ovlivněna genetickou dispozicí?
| Title in English | Is humoral activation in heart failure affected by genetic determination? |
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| Authors | |
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Cor et Vasa |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | Genetics-humoral activation-heart failure |
| Description | Aim of study: To document an association between the plasma levels of big endothelin and endothelin-1, clinical parameters and the two most frequent polymorphisms (-3A/-4A and G8002A) of the endothelin-1-encoding gene on the one hand and the plasma levels of TNF-alpha, clinical parameters and the gene polymorphisms of TNF-apha -308 A/G, -238 A/G, TNF-beta Ncol, and 3TACE (tumor necrosis factor-alpha-converting enzyme) in patients with chronic heart failure (HF). |
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