Two common polymorphisms within the adiponectin gene are associated with food preferences in extremely obese Czech individuals
| Title in English | TWO COMMON POLYMORPHISMS WITHIN THE ADIPONECTIN GENE ARE ASSOCIATED WITH FOOD PREFERENCES IN EXTREMELY OBESE CZECH INDIVIDUALS |
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| Authors | |
| Year of publication | 2008 |
| Type | Article in Proceedings |
| Conference | 1st Central European Congress on Obesity |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | adiponectin; polymorphism; extreme obesity; food preferences |
| Description | Objective: Considering the pivotal role of adiponectin in white adipose tissue metabolism and signaling, we assessed whether the 45T/G and 94T/G polymorphisms within the adiponectin gene influence the food preferences along with basic anthropometric characteristics in the Czech extremely obese population. Conclusions: Both examined polymorphism were significantly associated with various parametres of food intake, above all the total and relative intake of carbohydrates, which could provide possible explanation for the documented prodiabetogenic effects of these polymorphisms. The obtained results well fit into a framework for food intake regulation in relation to adiponectin role and could provide possible targets for further nutrigenomical research and intervention focused on the food preferences. |