Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear location of nestin

Warning

This publication doesn't include Faculty of Medicine. It includes Faculty of Science. Official publication website can be found on muni.cz.

Authors	LOJA Tomáš CHLAPEK Petr KUGLÍK Petr PEŠÁKOVÁ Martina OLTOVÁ Alexandra CEJPEK Pavel VESELSKÁ Renata
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Oncology Reports
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	nestin; CD133; intermediate filaments; glioblastoma multiforme; cancer stem cells; immunocytochemistry; transmission electron microscopy
Description	A detailed characterization of the established GM7 glioblastoma cell line is given in this paper. This cell line was identified as near-triploid and is characterized by nestin+/CD133+ phenotype with unusual localization of nestin both in cytoplasm and cell nucleus.
Related projects:	Gene Diagnostics and Therapy of Multiform Glioblastoma Molecular basis of cell and tissue regulations Molecular mechanisms of the cell proliferation and differentiation