Charakterizace interakce protilátek značených nanočásticemi s adukty PAH

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Title in English Characterization of antibody-labeled nanoparticles with PAH-adducts
Authors

PŘIBYL Jan SKLÁDAL Petr SUCHÁNEK Miloslav

Year of publication 2008
MU Faculty or unit

Faculty of Science

Description Characterization of antibodies labeled with nanopartilcles with PAH-adducts. Based on affinity biosensors and ELISA method. Its a manufacturing process. The process consists of immobilization of polyaromatic hydrocarbons conjugates onto solid surfaces (blotting membrane, biosensor surface, ELISA plate surface) followed by binding of modified nanoparticles. Such process leads to the detection limits improvement of bionalytical methods of one order of magnitude and also to the substantial reduction in use of bioreagents.
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