Free light chain ratio as a marker of complete remission

Authors

RADOCHA J MAISNAR Vladimír ZAHRADOVÁ Lenka HÁJEK R MACHÁLKOVÁ K VÁVROVÁ J TICHY M MALY J

Year of publication 2011
Type Conference abstract
Citation
Description Stringent complete remission (sCR) in multiple myeloma (MM) has been defined as complete remission (CR) with normal free light chain ratio (FLCr). However only a few studies have so far incorporated FLCr as the marker of the outcome in MM patients. Aim: Goal was to evaluate CR patients and compare the relapse rate in the group with normal FLCr and abnormal FLCr. Conclusion: So far only a few relapses occured, however it seems that in both groups the relapse rate seems to be the same regardless of FLCr status. Further longer follow-up is needed to confirm the significance of FLCr. Standardisation of methods used for FLCr evaluation is needed if we are to incorporate FLCr as a standard of CR evaluation.
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