Nanofibrous scaffolds for tissue engineering

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Authors	PAVLIŇÁK David ŠVACHOVÁ Veronika KEDROŇOVÁ Eva ALBERTI Milan HYRŠL Pavel DUŠKOVÁ Monika NEJEZCHLEBOVÁ Helena VOJTEK Libor
Year of publication	2011
Type	Article in Proceedings
Conference	Potencial and Applications of Surface Nanotreatment of Polymers and Glass
MU Faculty or unit	Faculty of Science
Citation
Keywords	tissue engineering;nanomaterial;nanotechnology;electrospinning;plasma-chemical treatment;bactericidal efect;bioactivity;chemical luminiscence
Description	Tissue engineering aims to develop biologically functional scafolds for the repair, replacement, or regeneration of damaged tissues. The aim of this work was to find a new manufacturing process of a biologically functional scaffolds. Various synthetic biopolymers, like a gelatine, PVA, collagen have been electrospun to satisfy different clinical requirments. The main research idea was to develop a suitable bactericidal agent that could be sufficiently biocompatible and biodegradable. These requirements fulfilled an oxycellulose which was produced using plasma-chemical reaction. Chemical composition of treated cellulose samples was evaluated with ATR-FTIR and TGA. Biological activity was evaluated by CL - chemical luminiscence methods.
Related projects:	Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface