Prevalence of Human Leukocyte Antigen (HLA)-B*5701 in HIV-infected subjects in Czech Republic.

• Authors: JILICH David; VRANÁ Milena; SNOPKOVÁ Svatava; SEDLÁČEK Dalibor; KAPLA Jaroslav; ROZSYPAL Hanuš; KOLČÁKOVÁ Jitka; OLBRECHTOVÁ Lenka; ZJEVÍKOVÁ Alena; JERHOTOVÁ Zdenka; MALÝ Marek; STAŇKOVÁ Marie; MACHALA Ladislav
• Year of publication: 2011
• Type: Article in Periodical
• Magazine / Source: Central European Journal of Public Health
• MU Faculty or unit: Faculty of Medicine
• Field: Epidemiology, infectious diseases and clinical immunology
• Keywords: Abacavir; Czech Republic; HLA-B*57:01; Hypersensitivity; Prevalence
• Description: The HLA-B*57:01 allele is associated with a hypersensitivity reaction to abacavir, and its prevalence varies in different populations. The aim of the study was to investigate HLA-B*57:01 prevalence in the Czech HIV-infected population. HLA-B*57:01 prevalence in our cohort was 5.33%, which is similar to the situation in other Central European countries